Proactive for invasion: Reuse of matrix metalloproteinase for structural memory
نویسندگان
چکیده
Migratory cells translocate membrane type-1 matrix metalloproteinase (MT1-MMP) to podosomes or invadosomes to break extracellular matrix barriers. In this issue, El Azzouzi et al. (2016.J. Cell. Biol.http://dx.doi.org/10.1083/jcb.201510043) describe an unexpected function for the MT1-MMP cytoplasmic domain in imprinting spatial memory for podosome reformation via assembly in membrane islets.
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عنوان ژورنال:
دوره 213 شماره
صفحات -
تاریخ انتشار 2016